Remodeling in asthma and COPD - differences and similarities
نویسندگان
چکیده
منابع مشابه
Similarities and differences in inflammatory mechanisms of asthma and COPD
Asthma and chronic obstructive pulmonary disease (COPD) are both characterised by airway obstruction, which is variable and reversible in asthma but is progressive and largely irreversible in COPD. In both diseases, there is chronic inflammation of the respiratory tract, which is mediated by the increased expression of multiple inflammatory proteins, including cytokines, chemokines, adhesion mo...
متن کاملAsthma and Chronic Obstructive Pulmonary Disease (COPD) – Differences and Similarities
Bronchial asthma and COPD (chronic obstructive pulmonary disease) are obstructive pulmonary diseases that affected millions of people all over the world. Asthma is a serious global health problem with an estimated 300 million affected individuals. COPD is one of the major causes of chronic morbidity and mortality and one of the major public health problems worldwide. COPD is the fourth leading ...
متن کاملAirway disease: similarities and differences between asthma, COPD and bronchiectasis
Airway diseases are highly prevalent worldwide; however, the prevalence of these diseases is underestimated. Although these diseases present several common characteristics, they have different clinical outcomes. The differentiation between asthma, chronic obstructive pulmonary disease and bronchiectasis in the early stage of disease is extremely important for the adoption of appropriate therape...
متن کاملAirway Remodelling in Asthma and COPD: Findings, Similarities, and Differences Using Quantitative CT
Airway remodelling is a well-established feature in asthma and chronic obstructive lung disease (COPD), secondary to chronic airway inflammation. The structural changes found on pathological examination of remodelled airway wall have been shown to display similarities but also differences. Computed tomography (CT) is today a remarkable tool to assess airway wall morphology in vivo since submill...
متن کاملAirway Epithelium in Atopic and Nonatopic Asthma: Similarities and Differences
Asthma is an inflammatory disorder of the airways, and the airway epithelium has the central role in its pathogenesis. In general, the airway inflammation is characterised by the infiltration of the epithelium and submucosa by a range of inflammatory cells driven largely by Th-2 lymphocytes, eosinophils, and mast cells. The pathogenic mechanisms of nonatopic asthma in comparison to its atopic c...
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ژورنال
عنوان ژورنال: The Clinical Respiratory Journal
سال: 2010
ISSN: 1752-6981,1752-699X
DOI: 10.1111/j.1752-699x.2010.00193.x